下記の通り創薬科学セミナー/GTRセミナー/CIBoGセミナーを開催します。多数のご参加をお待ちしております。
| 概要 | Guiding Cell Fate and Tissue Regeneration Using Biomimetic Scaffolds |
|---|---|
| 日時 | 2024年11月07日木曜日・16:00-17:30 |
| 場所 | 創薬科学研究館2F講義室 |
| 講師 | Sing Yian CHEW（The Sch. of Chemical and Biomedical Engineering, the Lee Kong Chian Sch. of Medicine and the Sch. of Materials Science and Engineering at Nanyang Technological Univ., Singapore/Professor） |
| 連絡先 | 加藤 竜司（kato-r@ps.nagoya-u.ac.jp） |
| ファイル | 173024882620241107_SouyakuSeminar190.pdf |
The extracellular matrix (ECM) microenvironment plays a crucial role in regulating cell fate and tissue regeneration. Therefore, designing tissue-engineered scaffolds that replicate the key biophysical and biochemical properties of the natural ECM can stimulate physiologically relevant cell and tissue responses. In this talk, we present our findings on biofunctional scaffold engineering, with a focus on incorporating biomolecules and utilizing RNA interference to promote nerve regeneration and remyelination. Specifically, we shall highlight fiber constructs that closely mimic the size and architecture of the native ECM, as well as 3D-printed scaffolds that will facilitate the design of patient-specific constructs and cell transplantation. Additionally, we shall discuss how the biophysical properties of scaffolds influence central nervous system regeneration and remyelination.
