| Laboratory | Members | Education, Research and Objectives |
|---|---|---|
| Laboratory of Process Chemistry SITE |
Professor : Shinichiro Fuse Assitant Professor : Naoto Yamasaki |
Realization of rapid, less expensive, and less wasteful production of pharmaceuticals is one of the most important tasks in a drug development field. Our group focuses on resolving this task based on the development of synthetic engineering technologies such as a continuous-flow synthesis technology and an automated synthesis technology. These technologies allow us to obtain a deeper understanding of organic reactions. Our group educates students through development of truly efficient synthetic processes. |
| Laboratory of Natural Products Chemistry SITE |
Professor : Satoshi Yokoshima Assistant Professor : Nariyoshi Umekubo |
Molecules isolated from natural sources, or natural products, exhibit a variety of bioactivities. Natural products have been used as medicines, and even now are important seeds for development of novel medicines. Our main task is total synthesis of natural products. Accomplishment of robust synthesis leads to providing necessary amounts of invaluable molecules for human beings. The synthetic routes thus established will expand our opportunity for creating related molecules with higher activity or functional tools to identify physiological targets of the natural products. |
| Laboratory of Molecular Design SITE |
Professor : Yoshihiko Yamamoto Assistant Professor : Takeshi Yasui |
The molecular design of candidate organic compounds that are expected to function as pharmaceutical agents plays an extremely important role in pharmaceutical sciences. During the development process from a candidate compound to the final pharmaceutical agent, both rational molecular design—which envisions derivatives with enhanced desired properties and reduced adverse drug reactions—and efficient synthesis of the final product are indispensable. Our laboratory implements creative research and education in molecular design chemistry, based on synthetic organic chemistry. This field endeavors to design new physiologically active molecules as part of the drug development pipeline. In addition, we emphasize the development of rational synthetic routes to generate these target compounds. |
