Masahiro YOSHIMURA (Associate Prof.)

CURRICULUM VITAE

Name:            Masahiro Yoshimura

Address:       Division of Liberal Arts and Sciences, Aichi Gakuin University,

                       12 Araike Iwasaki, Nisshin, Aichi 470-0195, Japan

TEL                     +81-561-73-1111 (ex. 3122)
FAX                     +81-561-73-1860

E-mail (primary):   yoshim@dpc.agu.ac.jp

Year of birth/place: 1973/Nagoya, Japan

Academic appointments:

2005–2008      Assistant Professor, Research Center for Materials Science, Nagoya University

2008–2013      Lecturer, Institute of Liberal Arts and Sciences, Nagoya University

2013–2021       Associate Professor, Division of Liberal Arts and Sciences, Aichi Gakuin University

2021–               Professor, Division of Liberal Arts and Sciences, Aichi Gakuin University

Education:

1995:               Bachelor: Nagoya University (Professors R. Noyori and M. Kitamura)

1997:               Master: Nagoya University (Professors R. Noyori and M. Kitamura)

2000:               Ph.D.: Nagoya University (Professors R. Noyori and M. Kitamura)

2000–2002:    Postdoctoral Fellow: Nagoya University (Professor M. Kitamura),

2002–2005:     Postdoctoral Fellow: Harvard University (Professor G. L. Verdine),

Award:

2007:               Nippon Shokubai Award in The Society of Synthetic Organic Chemistry, Japan

2011:               Japan e-Learning Awards (incentive award)

2020:               BCSJ Award Article in The Chemical Society of Japan

Memberships:

The Chemical Society of Japan

The Society of Synthetic Organic Chemistry, Japan

The American Chemical Society

Publications:

(1) Synthesis of α-Amino Phosphonic Acids by Asymmetric Hydrogenation. Kitamura, M.; Yoshimura, M.; Tsukamoto, M.; Noyori, R. Enantiomer 1996, 1, 281–303.

(2) Asymmetric Synthesis of β-Hydroxy Sulfonic Acids by BINAP/Ru-Catalyzed Hydrogenation. Kitamura, M.; Yoshimura, M.; Kanda, N.; Noyori, R. Tetrahedron 1999, 55, 8769–8785.

(3) Mechanism of Asymmetric Hydrogenation of α-(Acylamino)acrylic Esters Catalyzed by BINAP-Ruthenium(II) Diacetate. Kitamura, M.; Tsukamoto, M.; Bessho, Y.; Yoshimura, M.; Kobs, U.; Widhalm, M.; Noyori, R. J. Am. Chem. Soc. 2002, 124, 6649–6667.

(4)   Catalytic Leuckart-Wallach-Type Reductive Amination of Ketones. Kitamura, M.; Lee, D.; Hayashi, S.; Tanaka, S.; Yoshimura, M. J. Org. Chem. 2002, 67, 8685–8687.

(5)  (P(C₆H₅)₃)CpRu⁺-Catalyzed Deprotection of Allyl Carboxylic Esters. Kitamura, M.; Tanaka, S.; Yoshimura, M. J. Org. Chem. 2002, 67, 4975–4977.

(6) In Vitro Selection of RNA Aptamers Against a Composite Small Molecule-Protein Surface. Plummer, K. A.; Carothers, J. M.; Yoshimura, M.; Szostak, J. W.; Verdine, G. L. Nucleic Acids Research 2005, 33, 5602–5610.

(7) Origin of the Minor Enantiomeric Product in a Noyori Asymmetric Hydrogenation: Evidence that Mechanisms Different to the Major One Operate. Ishibashi, Y.; Bessho, Y.; Yoshimura, M.; Tsukamoto, M.; Kitamura, M. Angew. Chem. Int. Ed. 2005, 44, 7287–7290.

(8) Mechanism of Catalytic Asymmetric Hydrogenation of 2-Formyl-1-methylene-1,2,3,4-tetrahydroisoquinoline Using Ru(CH₃COO)₂[(S)-binap]. Tsukamoto, M.; Yoshimura, M.; Tsuda, K.; Kitamura, M. Tetrahedron 2006, 62, 5448–5453.

(9)   Catalytic Removal of N-Allyloxycarbonyl Groups Using the [CpRu(IV)(π-C₃H₅)(2-quinolinecarboxylato)]PF₆ Complex. A New Efficient Deprotecting Method in Peptide Synthesis. Tanaka, S.; Saburi, H.; Murase, T.; Yoshimura, M.; Kitamura, M. J. Org. Chem. 2006, 71, 4682–4684.

(10) Enantioselective Hydrogenation of Aromatic Ketones Catalyzed by Ru Complexes of Goodwin-Lions-type sp²N/sp³N Hybrid Ligands R-BINAN-R’-Py. Huang, H.; Okuno, T.; Tsuda, K.; Yoshimura, M.; Kitamura, M. J. Am. Chem. Soc. 2006, 128, 8716–8717.

(11) Enantiomeric Products Formed via Different Mechanisms: Asymmetric Hydrogenation of an α,β-Unsaturated Carboxylic Acid Involving a Ru(CH₃COO)₂[(R)-binap] Catalyst. Yoshimura, M.; Ishibashi, Y.; Miyata, K.; Bessho, Y.; Tsukamoto, M.; Kitamura, M. Tetrahedron 2007, 63, 11399–11409.

(12) Solvent-free One-pot Synthesis of Thallium Complexes of Tp [BH(Pz)₃]^– (Pz = pyrazolate) and its Derivatives. Tsuda, K.; Miyata, K.; Okuno, T.; Yoshimura, M.; Tanaka, S.; Kitamura, M. Tetrahedron Lett. 2008, 49, 2990–2993.

(13) Synthesis of 3,3′-Diaryl-Substituted 2,2′-Diamino-1,1′-Binaphthyl (diAr-BINAN) and Its Derivatives. Yoshimura, M.; Muraoka, T.; Huang, H.; Kitamura, M. J. Org. Chem. 2010, 75, 4315–4318.

(14) Desymmetric Hydrogenation of a meso-Cyclic Acid Anhydride toward Biotin Synthesis. Yoshimura, M.; Tsuda, K.; Nakatsuka, H.; Yamamura, T.; Kitamura, M. Tetrahedron 2011, 67, 10006–10010.

(15) Recent Topics in Catalytic Asymmetric Hydrogenation of Ketones. Yoshimura, M.; Tanaka, S.; Kitamura, M. Tetrahedron Lett. 2014, 55, 3635–3640.

(16) Asymmetric NaBH₄ 1,4-Reduction of C₃-Disubstituted 2-Propenoates Catalyzed by a Diamidine Cobalt Complex. Shuto, Y.; Yamamura, T.; Tanaka, S.; Yoshimura, M.; Kitamura, M. ChemCatChem 2015, 7, 1547–1550.

(17) Mechanism of Asymmetric Hydrogenation of Aromatic Ketones Catalyzed by a Combined System of Ru(π-CH₂C(CH₃)CH₂)₂(cod) and the Chiral sp²N/sp³NH Hybrid Linear N₄ Ligand Ph-BINAN-H-Py. Nakatsuka, H.; Yamamura, T.; Shuto, Y.; Tanaka, S.; Yoshimura, M.; Kitamura, M. J. Am. Chem. Soc. 2015, 137, 8138–8149.

(18) Revisiting the Cu^II-Catalyzed Asymmetric Friedel-Crafts Reaction of Indole with Trifluoropyruvate. Le, T. P.; Higashita, K.; Tanaka, S.; Yoshimura, M.; Kitamura, M. Org. Lett. 2018, 20, 7149–7153.

(19) Mechanism Change of (+)-Nonlinear Effect in a Phase Separation System in a Cu^II-Catalyzed Asymmetric Friedel-Crafts Reaction Using a C₂-Chiral Dioxolane-Containing-Bisamidine Ligand, Naph-diPIM-dioxo-iPr. Le, T. P.; Tanaka, S.; Yoshimura, M.; Kitamura, M. Bull. Chem. Soc. Jpn. 2020, 93, 1319–1333.

Review and Book Chapter

(1) Rhodium, Kitamura, M.; Yoshimura, M. In Handbook of Organometallic Reagents; Tamao, K. Ed.; Kagaku Dojin: Kyoto, 2003; pp176–182.

(2) Medicinal Chemistry through Asymmetric Hydrogenation. Yoshimura, M.; Kitamura, M. Sogo Rinsho 2008, 57, 125–131.

(3) Introductory Chemistry Laboratory Manual. Murata, S.; Urano, F.; Yoshimura, M. Nagoya University 2011, 1–95.

(4) Donor-Acceptor Bifunctional Molecular Catalyst: Its Development, Application, and Analysis. Kitamura, M.; Tanaka, S.; Yoshimura, M. J. Synth. Org. Chem., Jpn. 2015, 73, 690–700.

(5) Catalytic, Enantioselective, Transfer Hydrogenation. Yoshimura, M.; Kitamura, M. Organic Reaction 2019, 100, 329–382.