{"id":4474,"date":"2023-11-13T20:25:34","date_gmt":"2023-11-13T11:25:34","guid":{"rendered":"http:\/\/133.6.82.55\/lab_pages\/chemprocess\/?page_id=4474"},"modified":"2023-11-13T20:26:30","modified_gmt":"2023-11-13T11:26:30","slug":"kenkyugyoseki-gencho-2019","status":"publish","type":"page","link":"https:\/\/www.ps.nagoya-u.ac.jp\/lab_pages\/chemprocess\/kenkyugyoseki-gencho-2019\/","title":{"rendered":"\u540d\u53e4\u5c4b\u5927\u5b66\u5e03\u65bd\u7814\u7a76\u5ba4\u767a\u8db3\u524d\u306e\u539f\u8457\u8ad6\u6587 (original papers before moving to Nagoya University)"},"content":{"rendered":"\n

\u540d\u53e4\u5c4b\u5927\u5b66\u5e03\u65bd\u7814\u7a76\u5ba4\u767a\u8db3\u524d\u306e\u539f\u8457\u8ad6\u6587\uff08\uff5e2019.11.\uff09<\/strong><\/h4>\n

2019<\/span><\/a>\u00a0 2018<\/span><\/span><\/a>\u00a0 2017<\/span><\/span><\/a>\u00a0 2016<\/span><\/a>\u00a0 2015<\/span><\/span><\/a>\u00a0 2014<\/span><\/a>\u00a0 2013<\/span><\/a>\u00a0 2012<\/span><\/span><\/a>\u00a0 2011<\/span><\/a>\u00a0 2010<\/span><\/a>\u00a0 2009<\/span><\/a>\u00a0 \uff5e2008<\/span><\/span><\/a><\/strong><\/p>\n

70) Design, synthesis, and evaluation of indeno[2,1-c<\/em>]pyrazolones for use as inhibitors against hypoxia-inducible factor (HIF)-1 transcriptional activity,<\/p>\n

S. Fuse<\/strong>, K. Suzuki, T. Kuchimaru, T. Kadonosono, H. Ueda, S. Sato, S. Kizaka-Kondo, H. Nakamura,*<\/p>\n

Bioorg. Med. Chem.<\/em> 28<\/em>, 115207 (2020).<\/span><\/a><\/p>\n

69) The design, synthesis, and evaluation of azo D-\u03c0-A dyes as photothermal agents,
\u00a0<\/strong><\/p>\n

S. Fuse<\/strong>,* T. Oishi, K. Matsumura, Y. Hayashi, S. Kawauchi, H. Nakamura*<\/p>\n

Org. Biomol. Chem. 18<\/em>, (1), 93-101 (2020).<\/span><\/a>\u00a0<\/p>\n

<\/a>68) Peptide chain elongation using unprotected amino acids in a micro-flow reactor,
\u00a0<\/strong><\/p>\n

S. Fuse<\/strong>,* K. Masuda, Y. Otake, H. Nakamura<\/p>\n

Chem. Eur. J.<\/em> 25<\/em>, (66), 15091-15097 (2019).<\/span><\/a><\/p>\n

Inside Cover Picture<\/span><\/a>
\u00a0<\/em><\/strong><\/p>\n

Synfacts <\/em>01\/2020\u306b\u3066\u30cf\u30a4\u30e9\u30a4\u30c8
<\/span><\/strong>\u00a0<\/p>\n

67) Donor\u2013acceptor polymers containing thiazole-fused benzothiadiazole acceptor units for organic solar cells,\u00a0<\/p>\n

T. Nakamura, Y. Ishikura, N. Arakawa, M. Hori, M. Sato, M. Endo, H. Masui, S. Fuse<\/strong>, T. Takahashi, Y. Murata, R. Murdey, A. Wakamiya,*<\/p>\n

RSC Adv. <\/em>(9), 7107-7114 (2019).<\/span><\/a>\u00a0<\/p>\n

66) Elucidating the mode of action for thiophene-based organic D-\u03c0-A sensitizers for use in photodynamic therapy,
\u00a0<\/strong><\/p>\n

S. Fuse<\/strong>,* M. Takizawa, S. Sato, S. Okazaki, H. Nakamura,*<\/p>\n

Bioorg. Med. Chem. 27<\/em>, (2), 315-321 (2019).<\/span><\/a>\u00a0<\/p>\n

<\/a>65) Synthesis of 3-hydroxy-4-substituted-picolinonitriles from\u00a0<\/p>\n

4-propargylaminoisoxazoles via stepwise and one-pot isoxazolopyridine formation\/N-O bond cleavage sequence,\u00a0<\/p>\n

S. Fukuhara, S. Yugandar, S. Fuse<\/strong>, H. Nakamura,*<\/p>\n

ACS Omega <\/em>3<\/em>, (12), 16472-16476 (2018).<\/span><\/a>\u00a0<\/p>\n

64) The design, synthesis, and evaluation of organic dithienopyrrole-based D-\u03c0-A dyes for use as sensitizers in photodynamic therapy,
\u00a0<\/strong><\/p>\n

S. Fuse<\/strong>,* K. Matsumura, M. Takizawa, S. Sato, H. Nakamura,*<\/p>\n

Bioorg. Med. Chem. Lett. <\/em>28<\/em>, (18), 3099-3104 (2018).<\/span><\/a>\u00a0<\/p>\n

63) Rapid and mild synthesis of amino acid N<\/em>-carboxy anhydrides using basic-to-acidic flash switching in a micro-flow reactor,\u00a0<\/p>\n

Y. Otake, H. Nakamura, S. Fuse<\/strong>,*<\/p>\n

Angew. Chem. Int. Ed. <\/em>57<\/em>, (35), 11389-11393 (2018).<\/span><\/a>
\u3000<\/strong><\/p>\n

\u5316\u5b66\u5de5\u696d\u65e5\u5831\u63b2\u8f09\uff08<\/strong>H30\/8\/6<\/strong>\uff09
<\/strong>\u3000<\/em><\/strong><\/p>\n

Synfacts <\/em><\/strong>12\/2018<\/strong>\u306b\u3066\u30cf\u30a4\u30e9\u30a4\u30c8\u3000<\/strong><\/p>\n


<\/strong>62) Compact test set for sensitivity evaluation of photoacoustic contrast agent,<\/p>\n

X. Zeng,* Y. Mizuno, K. Nakamura, S. Fuse, H. Nakamura,<\/p>\n

Acoust. Sci. Technol.<\/em> 39, <\/em>(3), 259-262 (2018).<\/span><\/a><\/p>\n

61) Gold(I)-catalyzed intramolecular SEAr reaction: Efficient synthesis of isoxazole-containing fused heterocycles,<\/p>\n

T. Morita, S. Fukuhara, S. Fuse<\/strong>, H. Nakamura,*<\/p>\n

Org. Lett.<\/em> 20<\/em>, (2), 433-436 (2018).<\/span><\/a>
\u3000<\/em><\/strong><\/p>\n

Synfacts <\/em><\/strong>04\/2018<\/strong>\u306b\u3066\u30cf\u30a4\u30e9\u30a4\u30c8
<\/strong><\/p>\n

60) D\u2013\u03c0\u2013A dyes containing novel hydantoin anchoring groups for dye-sensitized solar cells,<\/p>\n

H. Masui, M. M. Maitani, S. Fuse<\/strong>, A. Yamamura, Y. Ogomi, S. Hayase, T. Kaiho, H. Tanaka, Y. Wada, T. Takahashi,*<\/p>\n

Asian J. Org. Chem.<\/em> 7<\/em>, (2), 458-464 (2018).<\/span><\/a><\/p>\n

59) Synthesis of pyrazolofuropyrazine via one-pot SNAr\u00a0 reaction\/intramolecular C-H direct arylation,
\u3000<\/strong><\/p>\n

S. Fuse<\/strong>,* M. Inaba, S. Sato, M. Joshi, H. Nakamura,*<\/p>\n

Synthesis <\/em>50<\/em>, (7), 1493-1498 (2018).<\/span><\/a><\/p>\n

<\/a>58) Photodynamic therapy using using a cytotoxic photosensitizer porphyrus envelope that targets the cell membrane<\/p>\n

M. Inai,* N. Honda, H. Hazama, S. Akter, S. Fuse<\/strong>, H. Nakamura, T. Nishikawa, Y. Kaneda, K. Awazu,<\/p>\n

Photodiag. Photodyn. Ther. <\/em>20<\/em>, 238-245 (2017).<\/span><\/a><\/p>\n

57) Thiophene-based, organic D-\u03c0-A dyes as potent sensitizers for photodynamic therapy,
\u3000<\/strong><\/p>\n

S. Fuse<\/strong>,* M. Takizawa, K. Matsumura, S. Sato, S. Okazaki, H. Nakamura,*<\/p>\n

Eur. J. Org. Chem.<\/em> (34), 5170-5177 (2017).<\/span><\/a><\/p>\n

56) Solution-phase automated synthesis of \u03b1-amino aldehyde as a versatile intermediate,<\/p>\n

H. Masui, S. Yosugi, S. Fuse<\/strong>, T. Takahashi,*<\/p>\n

Beilstein J. Org. Chem.<\/em>\u00a013<\/em>, 106-110 (2017).<\/span><\/a><\/p>\n

<\/a>55) A rapid and clean synthetic approach to cyclic peptides via micro-flow peptide chain elongation and photochemical cyclization: Synthesis of a cyclic RGD peptide,<\/p>\n

Y. Mifune, H. Nakamura, S. Fuse<\/strong>,*<\/p>\n

Org. Biomol. Chem. <\/em>14<\/em>, (47), 11244-11249 (2016).<\/span><\/a><\/p>\n

54) Development of 1-aryl-3-furanyl\/thienyl-imidazopyridine templates for inhibitors against hypoxia inducible factor (HIF)-1 transcriptional activity,
\u3000<\/strong><\/p>\n

S. Fuse<\/strong>, T. Ohuchi, Y. Asawa, S. Sato, H. Nakamura,*<\/p>\n

Bioorg. Med. Chem. Lett.<\/em> 26, <\/em>(24), 5887-5890 (2016).<\/span><\/a><\/p>\n

53) Total synthesis of feglymycin based on a linear\/convergent hybrid \u3000approach using micro-flow amide bond formation,
\u3000<\/strong><\/p>\n

S. Fuse<\/strong>,* Y. Mifune, H. Nakamura, H. Tanaka,<\/p>\n

Nat. Commun.<\/em> 7<\/em>, 13491, doi: 10.1038\/ncomms13491, (2016).<\/span><\/a>
\u3000<\/strong><\/p>\n

\u65e5\u7d4c\u7523\u696d\u65b0\u805e\u63b2\u8f09\uff08<\/strong>H28\/12\/2<\/strong>\uff09
<\/strong>\u3000<\/strong><\/p>\n

\u79d1\u5b66\u65b0\u805e\u63b2\u8f09\uff08<\/strong>H28\/12\/9<\/strong>\uff09
<\/strong>\u3000<\/strong><\/p>\n

ScienceNewline<\/strong>\u306b\u3066\u30cf\u30a4\u30e9\u30a4\u30c8
<\/strong>\u3000<\/strong><\/p>\n

PHYS ORG<\/strong>\u306b\u3066\u30cf\u30a4\u30e9\u30a4\u30c8
<\/strong>\u3000<\/strong><\/p>\n

Follow News<\/strong>\u306b\u3066\u30cf\u30a4\u30e9\u30a4\u30c8
<\/strong>\u3000<\/strong><\/p>\n

TECHNOLOGY TODAY<\/strong>\u306b\u3066\u30cf\u30a4\u30e9\u30a4\u30c8
<\/strong>\u3000<\/strong><\/p>\n

New-Medical.net<\/strong>\u306b\u3066\u30cf\u30a4\u30e9\u30a4\u30c8
<\/strong><\/p>\n

52) The design, synthesis, and evaluation of 1,5,7-trisubstituted-3-pyridyl-xanthones for use as insecticides starting from pyripyropene A,
\u3000<\/strong><\/p>\n

S. Fuse<\/strong>,* K. Matsumura, K. Johmoto, H. Uekusa, H. Tanaka, T. Hirose, T. Sunazuka, S. \u014cmura, T. Takahashi,<\/p>\n

Chem. Eur. J.<\/em> 22<\/em>, (51), 18450-18455 (2016).<\/span><\/a>
\u3000<\/strong><\/p>\n

Hot Paper<\/strong><\/p>\n

51) Generation of 4-isoxazolyl anion species: facile access to multi-functionalized isoxazoles,<\/p>\n

T. Morita, S. Fuse<\/strong>,* H. Nakamura,*<\/p>\n

Angew. Chem. Int. Ed. <\/em>55<\/em>, (43), 13580-13584 (2016).<\/span><\/a>
\u3000<\/em><\/strong><\/p>\n

Synfacts <\/em><\/strong>12\/2016<\/strong>\u306b\u3066\u30cf\u30a4\u30e9\u30a4\u30c8
<\/strong><\/p>\n

50) The synthesis of trans-flavan-3-ol gallates by regioselective oxidative etherification and their cytotoxicity mediated by 67LR,<\/p>\n

N. Shiraishi, M. Kumazoe, S. Fuse<\/strong>, H. Tachibana, H. Tanaka,*<\/p>\n

Chem. Eur. J. <\/em>22<\/em>, (37), 13050-13053 (2016).<\/span><\/a><\/p>\n

49) 6-Azido-6-deoxy-L-idose as a hetero-bifunctional spacer for the synthesis of azido-containing chemical probes,<\/p>\n

H. Hamagami, M. Kumazoe, Y. Yamaguchi, S. Fuse<\/strong>, H. Tachibana, H. Tanaka,*<\/p>\n

Chem. Eur. J. <\/em>22<\/em>, (36), 12884-12890 (2016).<\/span><\/a><\/p>\n

48) Synthesis of asymmetrically terminal bifunctionalized alkanes by sequential Suzuki-Miyaura coupling using B<\/em>-thexyl boracyclanes,<\/p>\n

R. Suzuki, S. Fuse<\/strong>, H. Tanaka,*<\/p>\n

Eur. J. Org. Chem. <\/em>(21), 3478-3481 (2016).<\/span><\/a><\/p>\n

47) The \u03b1-glycosidation of partially unprotected N<\/em>-acetyl and N<\/em>-glycolyl sialyl donors in the absence of a nitrile solvent effect,<\/p>\n

T. Aoyagi, S. Ohira, S. Fuse<\/strong>, J. Uzawa, Y. Yamaguchi, H. Tanaka,*<\/p>\n

Chem. Eur. J.<\/em> 22<\/em>, (20), 6968-6973 (2016).<\/span><\/a><\/p>\n

46) Synthesis of D-A\u2019-\u03c0-A dyes via one-pot three-component Suzuki-Miyaura coupling and an evaluation of the photovoltaic properties for use in DSSCs,<\/p>\n

S. Irie, S. Fuse<\/strong>,* M. M. Maitani, Y. Wada, Y. Ogomi, S. Hayase, T. Kaiho, H. Masui, H. Tanaka, T. Takahashi,<\/p>\n

Chem. Eur. J.<\/em> 22<\/em>, (7), 2507-2514 (2016).<\/span><\/a><\/p>\n

45) Synthesis and evaluation of thiophene-based organic dyes containing a rigid and non-planar donor with secondary electron Donors for use in dye-sensitized solar cells,
\u3000<\/strong><\/p>\n

S. Fuse<\/strong>,* R. Takahashi, M. M. Maitani, Y. Wada, T. Kaiho, H. Tanaka, T. Takahashi,<\/p>\n

Eur. J. Org. Chem.<\/em> (3), 508-517 (2016).<\/span><\/a><\/p>\n

<\/a>44) A facile preparation of \u03b1-aryl carboxylic acid via one-flow Arndt-Eistert synthesis,
\u3000<\/strong><\/p>\n

S. Fuse<\/strong>,* Y. Otake, Y. Mifune, H. Tanaka,<\/p>\n

Aust. J. Chem.<\/em> (invited) 68<\/em>, (11), 1657-1661 (2015).<\/span><\/a><\/p>\n

43) Directing group\/protecting group-free synthesis of tetraaryl-substituted pyrazoles via four direct arylations on an unsubstituted pyrazole scaffold,
\u3000<\/strong><\/p>\n

S. Fuse<\/strong>,* T. Morita, K. Johmoto, H. Uekusa, H. Tanaka,<\/p>\n

Chem. Eur. J.<\/em> 21<\/em>, (41), 14370-14375 (2015).<\/span><\/a>
\u3000<\/strong><\/p>\n

Hot Paper
<\/strong><\/p>\n

Inside <\/strong>Cover Picture<\/strong><\/span><\/a>
<\/strong><\/p>\n

42) Palladium-catalyzed double carbonylation-based diversity-oriented \u3000synthesis of 3,4-dihydroisoquinoline-1 -carboxamides,<\/p>\n

H. Masui, N. Ishizawa, S. Fuse<\/strong>, T. Takahashi,*<\/p>\n

Tetrahedron<\/em> 71<\/em>, (37), 6354-6360 (2015).<\/span><\/a>
\u3000<\/em><\/strong><\/p>\n

ChemInform 46<\/em><\/strong>, (44), (2015)<\/strong>\u306b\u3066\u30cf\u30a4\u30e9\u30a4\u30c8
<\/strong><\/p>\n

41) Regio-selective, one-pot, three-component synthesis of 1,3,4- and 1,3,5-triaryl pyrazoles from 1- and 2-aryl-1-alkenyl sulfones,
\u3000<\/strong><\/p>\n

S. Fuse<\/strong>,* H. Sugiyama, D. Kobayashi, Y. Iijima, K. Matsumura, H. Tanaka, T. Takahashi,<\/p>\n

Eur. J. Org. Chem.<\/em> (21), 4756-4764 (2015).<\/span><\/a><\/p>\n

40) Sequential SNAr reaction\/Suzuki-Miyaura coupling\/C-H direct arylations approach for the rapid synthesis of tetraaryl-substituted pyrazoles,<\/p>\n

T. Morita, D. Kobayashi, K. Matsumura, K. Johmoto, H. Uekusa, S. Fuse<\/strong>,* T. Takahashi,<\/p>\n

Chem. Asian J.<\/em> 10<\/em>, (8), 1626-1630 (2015).<\/span><\/a><\/p>\n

Cover Picture<\/strong><\/span><\/a>
<\/strong>\u3000<\/strong><\/p>\n

2015\/7-8 Most-accessed Articles
<\/strong>ChemInform 46<\/em><\/strong>, (52), (2015)<\/strong>\u306b\u3066\u30cf\u30a4\u30e9\u30a4\u30c8
<\/strong>Wiley Hottest Articles in Organic Chemistry<\/strong>\u306b\u9078\u5b9a
<\/strong><\/p>\n

39) Asymmetric total synthesis of ent<\/em>-pyripyropene A,
\u3000<\/strong><\/p>\n

S. Fuse<\/strong>,* A. Ikebe, K. Oosumi, T. Karasawa, K. Matsumura, M. Izumikawa, K. Johmoto, H. Uekusa, K. Shin-ya, T. Doi, T. Takahashi,*<\/p>\n

Chem. Eur. J. <\/em>21, <\/em>(26), 9454-9460, (2015).<\/span><\/a><\/p>\n

38) Rapid synthesis of thiophene-based, organic dyes for DSSCs via a one-pot, four-component coupling approach,<\/p>\n

K. Matsumura, S. Yoshizaki, M. M. Maitani, Y. Wada, Y. Ogomi, S. Hayase, T. Kaiho, S. Fuse<\/strong>,* H. Tanaka, T. Takahashi,<\/p>\n

Chem. Eur. J. <\/em>21,<\/em> (27) 9742-9747, (2015).<\/span><\/a><\/p>\n

37) Facile, one-step synthesis of 5-substituted thieno[3,4-c<\/em>]pyrrole-4,6-dione by palladium-catalyzed carbonylative amidation,
\u3000<\/strong><\/p>\n

S. Fuse<\/strong>,* R. Takahashi, T. Takahashi,<\/p>\n

Eur. J. Org. Chem. <\/em>(16), 3430-3434, (2015).<\/span><\/a>
\u3000<\/em><\/strong><\/p>\n

ChemInform 46<\/em><\/strong>, (39), (2015)<\/strong>\u306b\u3066\u30cf\u30a4\u30e9\u30a4\u30c8
<\/strong><\/p>\n

<\/a>36) Synthesis of EDOT-containing organic dyes via one-pot, four-component Suzuki-Miyaura coupling procedure and their evaluation of photovoltaic properties,
\u3000<\/strong><\/p>\n

S. Fuse<\/strong>,* Y. Asai, S. Sugiyama, K. Matsumura, M. M. Maitani, Y. Wada, Y. Ogomi, S. Hayase, T. Kaiho, T. Takahashi,*<\/p>\n

Tetrahedron<\/em> 70<\/em>, <\/em>(45), 8690-8695, (2014).<\/span><\/a><\/p>\n

35) Rapid library synthesis of amphiphiles based on a dioxinone scaffold and identification of nonlamellar liquid crystals,
\u3000<\/strong><\/p>\n

S. Fuse<\/strong>,* K. Nakamura, Y. Mifune, H. Marubayashi, I. Hijikuro, S. Nojima, H. Tanaka, T. Takahashi,<\/p>\n

Synlett<\/em>,25<\/em>, (19), 2806-2813, (2014).<\/span><\/a><\/p>\n

34) Elucidation of the structure-property relationship of p-type organic semiconductors through rapid library construction via a one-pot, Suzuki-Miyaura coupling reaction,
\u3000<\/strong><\/p>\n

S. Fuse<\/strong>,* K. Matsumura, A. Wakamiya, H. Masui, H. Tanaka, S. Yoshikawa,
T. Takahashi,<\/p>\n

ACS Comb. Sci. <\/em>16<\/em>, (9), 494-499, (2014).<\/span><\/a>
\u3000<\/strong><\/p>\n

2014\/8-9 Most-read Articles
<\/strong><\/p>\n

33) Total synthesis and stereochemistry revision of mannopeptimycin aglycone,
\u3000<\/strong><\/p>\n

S. Fuse<\/strong>,* H. Koinuma, A. Kimbara, M. Izumikawa, Y. Mifune, H. He, K. Shin-ya, T. Takahashi, T. Doi,*<\/p>\n

J. Am. Chem. Soc.<\/em> 136, <\/em>(34), 12011-12017, (2014).<\/span><\/a><\/p>\n

32) Development of dual targeting inhibitors against aggregations of amyloid-\u03b2 and tau protein,
\u3000<\/strong><\/p>\n

S. Fuse<\/strong>,* K. Matsumura, Y. Fujita, H. Sugimoto, T. Takahashi,<\/p>\n

Eur. J. Med. Chem.<\/em> 85<\/em>, 228-234, (2014).<\/span><\/a><\/p>\n

31) Synthesis of N<\/em>-allyloxycarbonyl 3,5-dihydroxyphenylglycine via photochemical Wolff rearrangement\/nucleophilic addition sequence in a micro-flow reactor,<\/p>\n

Y. Mifune, S. Fuse<\/strong>,* H. Tanaka<\/p>\n

J. Flow. Chem. <\/em>(Asia Special Issue, invited), 4<\/em>, (4), 173-179, (2014).<\/span><\/a><\/p>\n

30) Rapid and structurally diverse synthesis of multi-substituted \u03b2-keto
amide derivatives based on a dioxinone scaffold,
\u3000<\/strong><\/p>\n

S. Fuse<\/strong>,* H. Yoshida, K. Oosumi, T. Takahashi,<\/p>\n

Eur. J. Org. Chem.<\/em> (22), 4854-4860, (2014).<\/span><\/a><\/p>\n

29) Elucidating the structure-property relationship of donor-p-acceptor dyes for DSSCs through rapid\u00a0\u00a0\u00a0 library synthesis via a one-pot procedure,
\u3000<\/strong><\/p>\n

S. Fuse<\/strong>,* S. Sugiyama, M. M. Maitani, Y. Wada, Y. Ogomi, S. Hayase,
R. Katoh, T. Kaiho, T. Takahashi,<\/p>\n

Chem. Eur. J.<\/em> (Special Issue Young Chemist, invited), 20<\/em>, (34), 10685-10694, (2014).<\/span><\/a><\/p>\n

28) An efficient amide bond formation through the rapid and strong activation of carboxylic acids in a micro-flow reactor,
\u3000<\/strong><\/p>\n

S. Fuse<\/strong>,* Y. Mifune, T. Takahashi,<\/p>\n

Angew. Chem. Int. Ed. <\/em>53<\/em>, (3), 851-855, (2014).<\/span><\/a>
\u3000<\/strong><\/p>\n

\u5316\u5b66\u5de5\u696d\u65e5\u5831\u63b2\u8f09\uff08<\/strong>H26\/1\/24<\/strong>\uff09
<\/strong>\u3000<\/strong><\/p>\n

\u65e5\u520a\u5de5\u696d\u65b0\u805e\u63b2\u8f09\uff08<\/strong>H26\/1\/28<\/strong>\uff09
<\/strong>\u3000<\/strong><\/p>\n

\u79d1\u5b66\u65b0\u805e\u63b2\u8f09\uff08<\/strong>H26\/2\/7<\/strong>\uff09
<\/strong>\u3000<\/em><\/strong><\/p>\n

J. Flow Chem. 4, <\/em>(2), (2014)<\/strong>\u306b\u3066\u30cf\u30a4\u30e9\u30a4\u30c8
<\/strong>\u3000<\/em><\/strong><\/p>\n

ChemInform 45<\/em>, (30), (2014)<\/strong>\u306b\u3066\u30cf\u30a4\u30e9\u30a4\u30c8
<\/strong>\u3000<\/strong><\/p>\n

\u30d5\u30a1\u30eb\u30de\u30b7\u30a2<\/strong>, 50<\/em>, 103, (2014), <\/strong>\u30a8\u30c7\u30a3\u30bf\u30fc\u30ba\u30fb\u30a2\u30a4\u306b\u3066\u30cf\u30a4\u30e9\u30a4\u30c8
<\/strong>\u3000<\/strong><\/p>\n

\u65e5\u520a\u5de5\u696d\u65b0\u805e\u30d3\u30b8\u30cd\u30b9\u30e9\u30a4\u30f3\u306b\u3066\u30cf\u30a4\u30e9\u30a4\u30c8
<\/strong>\u3000<\/strong><\/p>\n

Wako Organic Square 53, <\/em>(2015)<\/strong>\u30da\u30d7\u30c1\u30c9\u5408\u6210\u306e\u6700\u8fd1\u306e\u9032\u6b69\u306b\u3066\u30cf\u30a4\u30e9\u30a4\u30c8
<\/strong><\/p>\n

27) Micro-flow synthesis and structural analysis of sterically crowded, \u3000diimine ligands with five aryl rings,
\u3000<\/strong><\/p>\n

S. Fuse<\/strong>,* N. Tanabe, A. Tannna, Y. Konishi, T. Takahashi,<\/p>\n

Beilstein J. Org. Chem.<\/em> 9<\/em>, 2336-2343, (2013).<\/span><\/a><\/p>\n

<\/a>26) Design and synthesis of 2-phenyl-1,4-dioxa-spiro[4.5]deca-6,9-dien-8-ones as potential anticancer agents starting from cytotoxic spiromamakone A,
\u3000<\/strong><\/p>\n

S. Fuse<\/strong>, K. Inaba, M. Takagi, M. Tanaka, T. Hirokawa, K. Johmoto, H. Uekusa, K. Shin-ya, T. Takahashi,* T. Doi,*<\/p>\n

Eur. J. Med. Chem.<\/em> 66<\/em>, 180-184, (2013).<\/span><\/a>\u00a0<\/p>\n

<\/a>25) A sequential coupling approach to the synthesis of nickel(II) complexes with N<\/em>-aryl-2-amino phenolates,
\u3000<\/strong><\/p>\n

S. Fuse<\/strong>, H. Tago, M. M. Maitani, Y. Wada, T. Takahashi,*<\/p>\n

ACS Comb. Sci.<\/em> 14<\/em>, (10), 545-550, (2012).<\/span><\/a><\/p>\n

24) A one-pot, three-component coupling approach to the synthesis of \u03b1-iminocarboxamides,<\/p>\n

H. Masui, S. Fuse<\/strong>, T. Takahashi,*<\/p>\n

Org. Lett.<\/em> 14<\/em>, (16), 4090-4093, (2012).<\/span><\/a>
\u3000<\/em><\/strong><\/p>\n

ChemInform 43<\/em><\/strong>, (51), (2012)<\/strong>\u306b\u3066\u30cf\u30a4\u30e9\u30a4\u30c8
<\/strong><\/p>\n

23) Continuous-flow synthesis of activated vitamin D3<\/sub> and its analogues,
\u3000<\/strong><\/p>\n

S. Fuse<\/strong>, Y. Mifune, N. Tanabe, T. Takahashi,*
\u3000<\/em><\/span><\/p>\n

Org. Biomol. Chem.<\/em> 10<\/em>, (27), 5205-5211, (2012).<\/span><\/a><\/p>\n

Cover Picture<\/strong><\/span><\/a>
<\/strong><\/p>\n

22) An iterative approach to the synthesis of thiophene-based organic dyes,
\u3000<\/strong><\/p>\n

S. Fuse<\/strong>, H. Yoshida, T. Takahashi,*<\/p>\n

Tetrahedron Lett.<\/em> 53<\/em>, (26), 3288-3291, (2012).<\/span><\/a><\/p>\n

21) Combinatorial synthesis and evaluation of \u03b1-iminocarboxamide-nickel (II) catalysts for the copolymerization of ethylene and a polar monomer,
\u3000<\/strong><\/p>\n

S. Fuse<\/strong>, H. Masui, A. Tannna, F. Shimizu, T. Takahashi,*<\/p>\n

ACS Comb. Sci.<\/em> 14<\/em>, (1), 17-24, (2012)<\/span><\/a>.<\/span>
<\/em>\u3000<\/strong><\/p>\n

2012\/1 Most-read Articles
<\/strong><\/p>\n

<\/a>20) Continuous in situ<\/em> generation and reaction of phosgene in a microflow system,
\u3000<\/strong><\/p>\n

S. Fuse<\/strong>, N. Tanabe, T. Takahashi,*<\/p>\n

Chem. Commun.<\/em> (47), 12661-12663, (2011)<\/span><\/a>.<\/span>
<\/em>\u3000<\/em><\/strong><\/p>\n

J. Flow Chem. 2, <\/em><\/strong>(1), (2012)<\/strong>\u306b\u3066\u30cf\u30a4\u30e9\u30a4\u30c8
<\/strong><\/p>\n

19) JBIR-56 and JBIR-57, 2(1H<\/em>)-pyrazinones from a marine sponge-derived Streptomyces<\/em> sp. SpD081030SC-03,<\/p>\n

K. Motohashi, K. Inaba, S. Fuse<\/strong>, T. Doi, M. Izumikawa, S. T. Khan, M. Takagi,* T. Takahashi, K. Shin-ya,*<\/p>\n

J. Nat. Prod.<\/em> 74<\/em>, (7), 1630-1635, (2011).<\/span><\/a>
\u3000<\/strong><\/p>\n

2011\/7 Most-read Articles
<\/strong><\/p>\n

18) Three-component coupling approach toward the synthesis of a resorcylic acid lactone framework,<\/p>\n

S. Sugiyama, S. Fuse<\/strong>, T. Takahashi,*<\/p>\n

Tetrahedron,<\/em> 67<\/em>, (35), 6654-6658, (2011).<\/span><\/a><\/p>\n

17) Ribosomal synthesis of backbone-macrocyclic peptides containing \u03b3-amino acids,<\/p>\n

Y. Ohshiro, E. Nakajima, Y. Goto, S. Fuse<\/strong>, T. Takahashi, T. Doi, H. Suga,*<\/p>\n

ChemBioChem<\/em>,12<\/em>, (8), 1183-1187, (2011).<\/span><\/a><\/p>\n

Cover Picture<\/strong><\/span><\/a>
<\/strong>\u3000<\/strong><\/p>\n

2011\/5 Most-accessed Articles
<\/strong><\/p>\n

16) Total synthesis of spiruchostatin B aided by an automated synthesizer,
\u3000<\/strong><\/p>\n

S. Fuse<\/strong>, K. Okada, Y. Iijima, A. Munakata, K. Machida, T. Takahashi,*
M. Takagi, K. Shin-ya, T. Doi,*<\/p>\n

Org. Biomol. Chem.<\/em> 9<\/em>, (3), 3825-3833, (2011).<\/span><\/a><\/p>\n

<\/a>15) Anti-influenza virus compound from Streptomyces <\/em>sp. RI18,<\/p>\n

M. Takagi,* K. Motohashi, A. Nagai, M. Izumikawa, M. Tanaka, S. Fuse<\/strong>, T.<\/p>\n

Doi, K. Iwase, A. Kawaguchi, K. Nagata, T. Takahashi, K. Shin-ya,*<\/p>\n

Org. Lett.<\/em> 12<\/em>, (20), 4664-4666, (2010)<\/span><\/a>.<\/span>
<\/em><\/p>\n

14) Continuous-flow synthesis of vitamin D3<\/sub>,
\u3000<\/strong><\/p>\n

S. Fuse<\/strong>, N. Tanabe, M. Yoshida, H. Yoshida, T. Doi, T. Takahashi,*<\/p>\n

Chem. Commun.<\/em> (46), 8722-8724, (2010).<\/span><\/a><\/p>\n

Inside Cover Picture<\/strong><\/span><\/a>
<\/strong>\u3000<\/em><\/strong><\/p>\n

Chem. Eng. News<\/em><\/strong> 2010, 88<\/em>, (51), Latest News<\/strong>\u306b\u3066\u30cf\u30a4\u30e9\u30a4\u30c8
<\/strong><\/p>\n

13) Rapid assembly of resorcylic acid lactone frameworks via sequential palladium-catalyzed coupling reactions,
\u3000<\/strong><\/p>\n

S. Fuse<\/strong>, S. Sugiyama, T. Takahashi,*<\/p>\n

Chem. Asian J. 5,<\/em>(3), 2459-2462, (2010).<\/span><\/a><\/p>\n

ChemInform 42<\/em><\/strong>, (18), (2011)<\/strong>\u306b\u3066\u30cf\u30a4\u30e9\u30a4\u30c8 <\/strong><\/p>\n


<\/strong>12) Synthesis of bicyclic enediynes that possess a photosensitive triggering device and exhibit strong DNA cleaving activity,<\/p>\n

H. Tanaka,* Y. Tanaka, M. Minoshima, S. Yamaguchi, S. Fuse<\/strong>, T. Doi, S. Kawauchi, H. Sugiyama T. Takahashi,*<\/p>\n

Chem. Commun.<\/em> (46), 5942-5944, (2010).<\/span><\/a><\/p>\n

11) Functional and structural analysis of a key region of the cell wall inhibitor moenomycin<\/span>,
\u3000<\/strong><\/p>\n

S. Fuse<\/strong>, H. Tsukamoto, Y. Yuan, T-S. Wang, Y. Zang, M. Bolla, S. Walker,* P. Sliz, D. Kahne,*<\/p>\n

ACS Chem. Biol.<\/em> 5<\/em>, (7), 701-711, (2010).<\/span><\/a>
\u3000<\/strong><\/p>\n

2010\/6 Most-accessed Articles
<\/strong><\/p>\n

10) Construction of the ABC ring system of taxanes via stereoselective one-pot three-component coupling and intramolecular alkylation of a protected cyanohydrin ether,<\/p>\n

T. Serizawa, S. Miyamoto, S. Fuse<\/strong>, T. Doi, T. Takahashi,*<\/p>\n

Bull. Chem. Soc. Jpn. <\/em>83<\/em>, (8), 942-949, (2010)<\/span><\/a>.<\/span>
<\/em>\u3000<\/em><\/strong><\/p>\n

ChemInform 41<\/em><\/strong>, (50), (2010)<\/strong>\u306b\u3066\u30cf\u30a4\u30e9\u30a4\u30c8
<\/strong><\/p>\n

9) Design, synthesis and evaluation of carbamate-modified (-)-N<\/em>1<\/sup>-phenetylnorphysostigmine derivatives as selective butyrylcholinesterase inhibitors,<\/p>\n

J. Takahashi, I. Hijikuro, T. Kihara, M. G. Murugesh, S. Fuse<\/strong>, Y. Tsumura, A. Akaike, T. Niidome, T. Takahashi, H. Sugimoto,*<\/p>\n

Bioorg. Med. Chem. Lett. <\/em>20<\/em>, (5), 1721-1723, (2010).<\/span><\/a><\/p>\n

8) Design, synthesis and evaluation and QSAR analysis of (-)-N<\/em>1<\/sup>-substituted
norcymserine derivatives as selective butyrylcholinesterase inhibitors,<\/p>\n

J. Takahashi, I. Hijikuro, T. Kihara, M. G. Murugesh, S. Fuse<\/strong>, R. Kunimoto, Y. Tsumura, A. Akaike, T. Niidome, Y. Okuno, T. Takahashi, H. Sugimoto,*<\/p>\n

Bioorg. Med. Chem. Lett. <\/em>20<\/em>, (5), 1718-1720, (2010).<\/span><\/a><\/p>\n

7) Development and application of a solution-phase automated synthesizer, \u2018ChemKonzert,\u2019<\/p>\n

K. Machida,* Y. Hirose, S. Fuse<\/strong>, T. Sugawara, T. Takahashi,<\/p>\n

Chem. Pharm. Bull.<\/em> 58<\/em>, (1), 87-93, (2010).<\/span><\/a><\/p>\n

<\/a>6) An efficient synthesis of a cyclic ether key intermediate for 9-membered masked enediyne using an automated synthesizer,<\/p>\n

Y. Tanaka, S. Fuse<\/strong>, H. Tanaka, T. Doi, T. Takahashi,*<\/p>\n

Org. Process Res. Dev.<\/em> 13<\/em>, (6), 1111-1121, (2009).<\/span><\/a><\/p>\n

5) Complete characterization of the seventeen step moenomycin biosynthetic pathway,<\/p>\n

B. Ostash, E. Doud, C. Lin, I. Ostash, D. Perlstein, S. Fuse<\/strong>, M. Wolpert, D. Kahne, S. Walker,*<\/p>\n

Biochemistry<\/em> 48<\/em>, (37), 8830-8841, (2009).<\/span><\/a><\/p>\n

4) Stereoselective one-pot three-component coupling approach toward the synthesis of the AC ring system of taxanes,<\/p>\n

T. Serizawa, S. Miyamoto, Y. Numajiri, S. Fuse<\/strong>, T. Doi, T. Takahashi,*<\/p>\n

Tetrahedron Lett.<\/em> 50<\/em>, (26), 3408-3410, (2009).<\/span><\/a><\/p>\n

<\/a>3) Structural analysis of the contacts anchoring moenomycin to peptidoglycan glycosyltransferases and implications for
antibiotic design,<\/p>\n

Y. Yuan, S. Fuse<\/strong>, B. Ostash, P. Sliz, D. Kahne,* S. Walker,\u00a0<\/p>\n

ACS Chem. Biol.<\/em> 3<\/em>, (7), 429-436, (2008).<\/span><\/a><\/p>\n

2) A formal total synthesis of taxol aided by an automated synthesizer,<\/p>\n

T. Doi, S. Fuse<\/strong>, S. Miyamoto, K. Nakai, D. Sasuga, T. Takahashi,*<\/p>\n

Chem. Asian J.<\/em> 1<\/em>, (3), 370-383, (2006).<\/span><\/a>
\u3000<\/strong><\/p>\n

3\/2006-7\/2007 Most-accessed Article
<\/strong>\u3000<\/em><\/strong><\/p>\n

\u30d5\u30a1\u30eb\u30de\u30b7\u30a2<\/em><\/strong>, 43<\/em>, 461, (2007)<\/strong>\u30c8\u30d4\u30c3\u30af\u30b9<\/strong>\u306b\u3066\u30cf\u30a4\u30e9\u30a4\u30c8
<\/strong><\/p>\n

1) Ti(III) catalyzed radical cyclization of 6,7-epoxygeranyl acetate,
\u3000<\/strong><\/p>\n

S. Fuse<\/strong>, M. Hanochi, T. Doi, T. Takahashi,*
<\/strong><\/p>\n

Tetrahedron Lett.<\/em>45<\/em>, (9), 1961-1963, (2004).<\/a>
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<\/p>\n","protected":false},"excerpt":{"rendered":"\u540d\u53e4\u5c4b\u5927\u5b66\u5e03\u65bd\u7814\u7a76\u5ba4\u767a\u8db3\u524d\u306e\u539f\u8457\u8ad6\u6587\uff08\uff5e2019.11.\uff09 2019\u00a0 2018\u00a0 2017\u00a0 2016\u00a0 2015\u00a0 2014\u00a0 2013\u00a0 2012\u00a0 2011\u00a0 2010\u00a0 2009\u00a0 \uff5e2008 70) Desi […]

\u7d9a\u304d\u3092\u8aad\u3080…<\/a><\/p>","protected":false},"author":15,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_locale":"ja","_original_post":"http:\/\/133.6.82.55\/lab_pages\/chemprocess\/?page_id=4474"},"_links":{"self":[{"href":"https:\/\/www.ps.nagoya-u.ac.jp\/lab_pages\/chemprocess\/wp-json\/wp\/v2\/pages\/4474"}],"collection":[{"href":"https:\/\/www.ps.nagoya-u.ac.jp\/lab_pages\/chemprocess\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.ps.nagoya-u.ac.jp\/lab_pages\/chemprocess\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.ps.nagoya-u.ac.jp\/lab_pages\/chemprocess\/wp-json\/wp\/v2\/users\/15"}],"replies":[{"embeddable":true,"href":"https:\/\/www.ps.nagoya-u.ac.jp\/lab_pages\/chemprocess\/wp-json\/wp\/v2\/comments?post=4474"}],"version-history":[{"count":2,"href":"https:\/\/www.ps.nagoya-u.ac.jp\/lab_pages\/chemprocess\/wp-json\/wp\/v2\/pages\/4474\/revisions"}],"predecessor-version":[{"id":4476,"href":"https:\/\/www.ps.nagoya-u.ac.jp\/lab_pages\/chemprocess\/wp-json\/wp\/v2\/pages\/4474\/revisions\/4476"}],"wp:attachment":[{"href":"https:\/\/www.ps.nagoya-u.ac.jp\/lab_pages\/chemprocess\/wp-json\/wp\/v2\/media?parent=4474"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}