{"id":4236,"date":"2023-07-24T12:56:51","date_gmt":"2023-07-24T03:56:51","guid":{"rendered":"http:\/\/133.6.82.55\/lab_pages\/chemprocess\/?page_id=4236"},"modified":"2023-07-24T13:03:06","modified_gmt":"2023-07-24T04:03:06","slug":"microflowgousei","status":"publish","type":"page","link":"https:\/\/www.ps.nagoya-u.ac.jp\/lab_pages\/chemprocess\/en\/kenkyushokai-en-2\/microflowgousei\/","title":{"rendered":"Micro-Flow Synthesis"},"content":{"rendered":"\n<p>\u00a0\u00a0 Synthetic chemists have used flasks to carry out reactions. At least, several seconds are required to complete a mixing of solutions in a flask, even under vigorous stirring conditions. Therefore, the precise control of short reaction time (&lt; <em>ca<\/em>. 60 sec)\u00a0 is very difficult using flasks.<br \/>\u00a0\u00a0 Micro-flow synthesis uses thin channels (inner diameter &lt; <em>ca<\/em>. 1mm) to carry out reactions. Rapid mixing (&lt; several milli seconds) can be readily performed using the micro-flow synthesis. For instance, we can obtain a rapidly mixed solution (light blue) from outlet of a T-shape mixer shown below by injecting two solutions (red and blue) into inlets of the T-shape mixer at high flow rates. In addition, temperature of the solution can be precisely controlled under micro-flow conditions due to large surface-to-volume ratio compared with that of batch conditions (flask).<\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" width=\"227\" height=\"189\" src=\"http:\/\/133.6.82.55\/lab_pages\/chemprocess\/wp-content\/uploads\/2023\/07\/1690166172.jpg\" alt=\"\" class=\"wp-image-4171\"\/><\/figure>\n\n\n\n<p>\u00a0\u00a0 There are many organic transformations that occur side reactions without precisely controlling the short reaction time (&lt; 60 sec). These transformations have been considered to be useless in synthetic organic chemistry. We have tried to create values of these reactions by the use of micro-flow technology.<\/p>\n","protected":false},"excerpt":{"rendered":"\u00a0\u00a0 Synthetic chemists have used flasks to carry out reactions. At least, several seconds are required to compl [&#8230;]<p><a class=\"btn btn-secondary understrap-read-more-link\" href=\"https:\/\/www.ps.nagoya-u.ac.jp\/lab_pages\/chemprocess\/en\/kenkyushokai-en-2\/microflowgousei\/\">\u7d9a\u304d\u3092\u8aad\u3080&#8230;<\/a><\/p>","protected":false},"author":15,"featured_media":0,"parent":4230,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_locale":"en_US","_original_post":"http:\/\/133.6.82.55\/lab_pages\/chemprocess\/?page_id=4170"},"_links":{"self":[{"href":"https:\/\/www.ps.nagoya-u.ac.jp\/lab_pages\/chemprocess\/wp-json\/wp\/v2\/pages\/4236"}],"collection":[{"href":"https:\/\/www.ps.nagoya-u.ac.jp\/lab_pages\/chemprocess\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.ps.nagoya-u.ac.jp\/lab_pages\/chemprocess\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.ps.nagoya-u.ac.jp\/lab_pages\/chemprocess\/wp-json\/wp\/v2\/users\/15"}],"replies":[{"embeddable":true,"href":"https:\/\/www.ps.nagoya-u.ac.jp\/lab_pages\/chemprocess\/wp-json\/wp\/v2\/comments?post=4236"}],"version-history":[{"count":2,"href":"https:\/\/www.ps.nagoya-u.ac.jp\/lab_pages\/chemprocess\/wp-json\/wp\/v2\/pages\/4236\/revisions"}],"predecessor-version":[{"id":4253,"href":"https:\/\/www.ps.nagoya-u.ac.jp\/lab_pages\/chemprocess\/wp-json\/wp\/v2\/pages\/4236\/revisions\/4253"}],"up":[{"embeddable":true,"href":"https:\/\/www.ps.nagoya-u.ac.jp\/lab_pages\/chemprocess\/wp-json\/wp\/v2\/pages\/4230"}],"wp:attachment":[{"href":"https:\/\/www.ps.nagoya-u.ac.jp\/lab_pages\/chemprocess\/wp-json\/wp\/v2\/media?parent=4236"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}